The effective delivery of anticancer drugs remains a critical clinical challenge due to factors such as degradation in biological environments, limited tumor penetration, and poor targeting of cancer cells. Specifically, in non-muscle invasive bladder cancer (NMIBC), the efficacy of intravesical therapies is further compromised by drug sedimentation and rapid elimination from the bladder via...
In equilibrium statistical physics, the fluctuation-compressibility theorem states that the variance of the number of particles, in a region of space with size $R$ , scales as $σ_N∼R^d$, with d the spatial dimension. Active systems, however, often exhibit giant number fluctuations (GNF), where $σ_N∼R^d$, with $β>d$. In contrast, when $β
Diatom frustules are porous bio-derived silica microstructures with potential as active micro/nanosystems. However, their insulating nature prevents direct electrodeposition, limiting their functionalization with magnetic materials. Here, we introduce a conductive platform to enable iron electrodeposition onto frustules while preserving their native porosity. Polycarbonate membranes were first...
Collective motion is a hallmark of active systems, yet most models of flocking use overdamped dynamics with instantaneous alignment. In this work we investigate how introducing rotational inertia modifies the flocking transition using underdamped Langevin dynamics framework with torque-based alignment interaction. Compared to overdamped orientational dymanics where stronger alignment...
Three-dimensional Covalent Organic Frameworks (3D COFs) possess highly tunable porous structures that hold immense potential for advanced device applications. However, their integration into active nano- and microsystems is currently bottlenecked by conventional solvothermal synthesis methods. These traditional approaches require prolonged reaction times (>12 h) and typically yield...
Nanoconfined water plays a crucial role in nanofluidics, biology, and cutting-edge technologies. The process of melting water monolayers and quasi-two-dimensional confined water involves, as an intermediate stage, the hexatic phase—a state that lies between solid and liquid and is characterized by quasi-long-range orientational order and short-range translational order. However, the influence...
Stimuli-responsive supramolecular materials are smart materials whose molecular organization, and consequently their properties can be controlled using external triggers such as temperature, pH, and light. In recent years, significant efforts have been devoted into developing active liposomes with precisely controllable structural properties. These systems can be leveraged for the programmable...
Metal–organic frameworks (MOFs) are porous coordination polymers characterized by high surface areas and broad application potential, particularly in biomedicine. However, their conventional synthesis often relies on dangerous organic solvents such as N,N-dimethylformamide (DMF), N,N-dimethylacetamide (DMA), and N,N-diethylformamide (DEF)[1, 2]. Among these materials, MIL-53 (Fe) was selected...
