Computational Modelling of Protein Corona Formation on Lipid Nanoparticles: Hard Corona and Polydispersity Effects
Fiona Gallach1,2*, Oriol Vilanova1,2, Alberto Martinez-Serra3, Marco Monopoli4, Giancarlo Franzese1,2
1Departament de Física de la Matèria Condensada, Facutat de Física, Universitat de Barcelona, Marti i Franques 1, 08028 Barcelona, Spain
2Institute of Nanoscience and...
Morphological control of crystals is utterly important in reticular chemistry, especially as a fundamental strategy toward preparing functional materials of superior properties. Despite the notable advancements in the realm of metal-organic frameworks (MOFs), where endeavors primarily focus on shape manipulation at the nano- and microscale during bulk synthesis and subsequent processing at the...
Microorganisms and microscale entities swimming in fluids at low Reynolds number (Re) need to devise innovative ways of propulsion to avoid reciprocal motion [1]. A way to break the time-reversible nature of fluid flow at low Re is to use the proximity of a boundary surface. In this work, we design an innovative S-shape micro propeller that rises and levitates from a close plane due to...
Hydrogels are hydrophilic polymeric networks characterized by high water content, permeability, and tunable properties, which make them attractive materials for biomedical applications such as drug delivery, tissue engineering, wound healing, biosensors, bioinks, and catalysis.
Within this framework, peptide‑based hydrogels are particularly appealing due to their mild fabrication...
Light-activated Janus microswimmers offer a programmable active-matter platform in which illumination modulates propulsion and enables controlled density modulations and localization [1,2]. We develop a continuum theory model that captures swimming pressure and the resulting dynamic pattern formation in spatially structured activity landscapes. Our framework couples a conservation law for the...
The study of the formation of condensed, self-ordered phases has remained a central focus in the fields of condensed matter physics and particle physics over the past few decades. Examples of systems capable of forming ordered phases under confinement include electrons on the surface of liquid helium, electrons in quantum dots, and charged particles suspended in plasma1,2. A common...
We experimentally, numerically and analytically explore the diffusive transport of active colloidal particles with sensory delay, navigating motility landscapes in which the self--propulsion speed depends on space. We show how the transport properties can be obtained by replacing the space dependence of the self--propulsion speed by a dynamical stochastic switching process in the absence of...
Many soft and biological systems operate in ionic environments where salts significantly influence water transport and stability. In aqueous electrolyte solutions, viscosity and diffusivity are often described by the empirical Jones–Dole relation and commonly discussed in terms of structure-making (kosmotropic) or structure-breaking (chaotropic) ions [1]. However, the physical basis and the...
