24–25 Oct 2024
Barcelona
CET timezone

Sperm-driven micromotors moving in complex environments and their potential biomedical applications

24 Oct 2024, 12:30
30m
Faculty of Chemistry / Enric Casassas, Aula Magna (Barcelona)

Faculty of Chemistry / Enric Casassas, Aula Magna

Barcelona

Plenary talk Plenary Talks (II)

Speaker

Mariana Medina-Sanchez (CIC nanoGUNE BRTA)

Description

Several concepts have been pursued by different research groups worldwide to realize untethered propulsion on a small size scale. Potential geometries for such untethered devices range from tubular microjets, Janus particles, or rods, over bio-inspired artificial flagella, to helical micromotors. Physical micromotors and microrobots for example are based on external physical fields such as magnetic fields and ultrasound, while the bio-hybrid micromotors mainly rely on the propulsion ability of the coupled biological entity (e.g. sperm, bacteria). In particular, I am going to talk about sperm-hybrid microrobots designed to increase the pregnancy success rate and reduce the invasiveness of current assisted fertilization technologies. These sperm-hybrid microrobots have also been used as drug carriers for gynecological cancer treatment. Finally, to translate these technologies to pre-clinical trials, we have recently reported the successful tracking of magnetically-driven micromotors in phantom, ex-vivo, and living mice with high spatial and temporal resolution employing photoacoustic imaging

Primary author

Mariana Medina-Sanchez (CIC nanoGUNE BRTA)

Presentation materials

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